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KMID : 0360220080490010164
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 1 p.164 ~ p.168
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A Case Report of Fungal Keratitis Diagnosed by Femtosecond Laser Assisted Corneal Biopsy
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Yum Jung-Hoon
Choi Suk-Kyue
Lee Jong-Hyun
Lee Do-Hyung
Kim Jin-Hyoung
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Abstract
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Purpose : To describe femtosecond laser-assisted corneal biopsy and its use in assessing the causative
organism in a case of fungal keratitis that occurred 8 months after penetrating keratoplasty.
Case summary : A 27-year-old man who had undergone penetrating keratoplasty 8 months prior showed
atypical diffuse corneal haze and erosion. Diagnostic corneal biopsy using a femtosecond laser was performed
because of repeated negative test results for an infectious organism and a lack of improvement, despite steroid
and empirical antibiotic therapy. A corneal flap 200 μm in depth and 3 mm in diameter was obtained. The
biopsy showed pseudohyphae, which led to a diagnosis of Candidal keratitis. No complications occurred
during the procedure.
Conclusion : Femtosecond laser-assisted corneal biopsy enabled identification of the infectious pathogen. This
technique is easy, safe, and rapid, and it yields a biopsy specimen with a uniform depth and precise size.
Femtosecond laser-assisted corneal biopsy can be used as an accurate diagnostic method in uncertain cases
of corneal ulcers.
J Korean Ophthalmol Soc 49(1):164-168, 2008
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KEYWORD
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Corneal biopsy, Femtosecond Laser, Fungal keratitis
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